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1

ChemInform Abstract: Synthesis of Substituted 5[H]Phenanthridin-6-ones as Potent Poly(ADP-ribose)polymerase-1 (PARP1) Inhibitors.

Jia-He Li, Larisa Serdyuk, Dana V. Ferraris, Ge Xiao, Kevin L. Tays, Paul W. Kletzly, Weixing Li, Susan Lautar, Jie Zhang, Vincent J. Kalish

Journal:

Year:

2001

File:

PDF, 26 KB

2001

2

Design and Synthesis of Poly(ADP-ribose)polymerase-1 (PARP-1) Inhibitors. Part 3. In vitro Evaluation of 1,3,4,5-Tetrahydro-benzo[c][1,6]- and [c][1,7]-naphthyridin-6-ones.

Dana Ferraris, Rica Pargas Ficco, Thomas Pahutski, Susan Lautar, Shirley Huang, Jie Zhang, Vincent Kalish

Journal:

Year:

2003

File:

PDF, 155 KB

2003

3

A Yeast Three-Hybrid Method to Clone Ternary Protein Complex Components

Jie Zhang, Susan Lautar

Journal:

Analytical Biochemistry

Year:

1996

Language:

english

File:

PDF, 234 KB

english, 1996

4

Ketopyrrolidines and ketoazetidines as potent dipeptidyl peptidase IV (DPP IV) inhibitors

Dana Ferraris, Yao-Sen Ko, David Calvin, Tiffany Chiou, Susan Lautar, Bert Thomas, Krystyna Wozniak, Camilo Rojas, Vincent Kalish, Sergei Belyakov

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 319 KB

english, 2004

5

Synthesis of substituted 5[H]phenanthridin-6-ones as potent poly(ADP-ribose)polymerase-1 (PARP1) inhibitors

Jia-He Li, Larisa Serdyuk, Dana V. Ferraris, Ge Xiao, Kevin L. Tays, Paul W. Kletzly, Weixing Li, Susan Lautar, Jie Zhang, Vincent J. Kalish

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 149 KB

english, 2001

6

Design and synthesis of poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors. Part 3: In vitro evaluation of 1,3,4,5-Tetrahydro-benzo[c][1,6]- and [c][1,7]-naphthyridin-6-ones

Dana Ferraris, Rica Pargas Ficco, Thomas Pahutski, Susan Lautar, Shirley Huang, Jie Zhang, Vincent Kalish

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 224 KB

english, 2003

7

Design and synthesis of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. part 4: Biological evaluation of imidazobenzodiazepines as potent PARP-1 inhibitors for treatment of ischemic injuries

Dana Ferraris, Rica Pargas Ficco, David Dain, Mark Ginski, Susan Lautar, Kathy Lee-Wisdom, Shi Liang, Qian Lin, May X.-C Lu, Lisa Morgan, Bert Thomas, Lawrence R Williams, Jie Zhang, Yinong Zhou, Vinc

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 416 KB

english, 2003

8

DPP IV inhibitor blocks mescaline-induced scratching and amphetamine-induced hyperactivity in mice

Susan L. Lautar, Camilo Rojas, Barbara S. Slusher, Krystyna M. Wozniak, Ying Wu, Ajit G. Thomas, Daniel Waldon, William Li, Dana Ferraris, Sergei Belyakov

Journal:

Year:

2005

Language:

english

File:

PDF, 327 KB

english, 2005

9

GPI 6150 Prevents H2O2 Cytotoxicity by Inhibiting Poly(ADP-ribose) Polymerase

Jie Zhang, Susan Lautar, Shirley Huang, Cynthia Ramsey, Anissa Cheung, Jia-He Li

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 272 KB

english, 2000

10

Design and Synthesis of Poly ADP-ribose Polymerase-1 Inhibitors. 2. Biological Evaluation of Aza-5[ H ]-phenanthridin-6-ones as Potent, Aqueous-Soluble Compounds for the Treatment of Ischemic Injuries

Ferraris, Dana, Ko, Yao-Sen, Pahutski, Thomas, Ficco, Rica Pargas, Serdyuk, Larisa, Alemu, Christina, Bradford, Chadwick, Chiou, Tiffany, Hoover, Randall, Huang, Shirley, Lautar, Susan, Liang, Shi, Li

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 222 KB

english, 2003

11

Ligand autoradiographic receptor screening: receptor cDNA expression in replicas of transfected COS cells

Rattray, Marcus, Lautar, Susan L., Uhl, George R.

Journal:

Molecular Brain Research

Year:

1990

Language:

english

File:

PDF, 3.84 MB

english, 1990

12

Azetidine-Based Inhibitors of Dipeptidyl Peptidase IV (DPP IV)

Ferraris, Dana, Belyakov, Sergei, Li, Weixing, Oliver, Eddie, Ko, Yao-Sen, Calvin, David, Lautar, Susan, Thomas, Bert, Rojas, Camilo

Journal:

Current Topics in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 1.06 MB

english, 2007

13

GPI 6607, A WATER-SOLUBLE POLY(ADP-RIBOSE) POLYMERASE INHIBITOR PROTECTS AGAINST SPLANCHNIC ARTERY OCCLUSION AND REPERFUSION INJURY IN RATS.

Mooney, Maria L., Shea-Donohue, Terez, Tran, Scott B., Xiao, Ge, Li, Jia-He, Lautar, Susan, Zhang, Jie, Wu, Qi Yi

Journal:

Year:

2002

File:

PDF, 894 KB

2002

14

A new method of screening receptor cDNAs: influence of plasmid competition on receptor expression

RATTRAY, MARCUS, LAUTAR, SUSAN L., UHL, GEORGE R.

Journal:

Biochemical Society Transactions

Year:

1989

Language:

english

File:

PDF, 269 KB

english, 1989